Antibodies that detect Claudin 4 can be used in several scientific applications, including Immunohistochemistry, Western Blot, ELISA, Immunocytochemistry and Immunoprecipitation. These antibodies target Claudin 4 in Human, Mouse, Rat, Canine and Non-human primate samples. Our...Antibodies that detect Claudin 4 can be used in several scientific applications, including Immunohistochemistry, Western Blot, ELISA, Immunocytochemistry and Immunoprecipitation. These antibodies target Claudin 4 in Human, Mouse, Rat, Canine and Non-human primate samples. Our Claudin 4 polyclonal, monoclonal and recombinant...Antibodies that detect Claudin 4 can be used in several scientific applications, including Immunohistochemistry, Western Blot, ELISA, Immunocytochemistry and Immunoprecipitation. These antibodies target Claudin 4 in Human, Mouse, Rat, Canine and Non-human primate samples. Our Claudin 4 polyclonal, monoclonal and recombinant monoclonal antibodies are developed in Rabbit and Mouse. These antibodies have been verified by Cell treatment, Knockdown and Relative expression to confirm specificity to Claudin 4. Find the Claudin 4 antibody that fits your needs. Choose from 1 of 17 Claudin 4 antibodies, which have been validated in experiments with 514 publications and 124 images featured in our data gallery.
Browse primary...
Antibodies that detect Claudin 4 can be used in several scientific applications, including Immunohistochemistry, Western Blot, ELISA, Immunocytochemistry and Immunoprecipitation. These antibodies target Claudin 4 in Human, Mouse, Rat, Canine and Non-human primate samples. Our Claudin 4 polyclonal, monoclonal and recombinant monoclonal antibodies are developed in Rabbit and Mouse. These antibodies have been verified by Cell treatment, Knockdown and Relative expression to confirm specificity to Claudin 4. Find the Claudin 4 antibody that fits your needs. Choose from 1 of 17 Claudin 4 antibodies, which have been validated in experiments with 514 publications and 124 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you’re looking for, contact us today to develop custom antibodies for specific targets, species and applications.
靶标信息
Claudin-4 belongs to the 20-member family of claudins, transmembrane cellular adhesion proteins localized at epithelial and endothelial tight junctions. Claudins demonstrate distinct, tissue-specific expression patterns, and are essential components of tight junction charge-specific channels that regulate paracellular ion flux. Claudin-4 is a component of tight junction strands and may play a role in internal organ development and function during pre- and postnatal life. The overexpression of Claudin-4 has been shown to decrease paracellular electrical conductance due to a selective decrease in Na+ permeability, with no significant decrease in Cl- permeability. In ovarian carcinoma cells, Claudin-3 and Claudin-4 exhibit upregulation at both mRNA and protein levels. Claudin-4 is also overexpressed in pancreatic cancer tissues and cell lines, and in other epithelial cancers. The Claudin-4 gene is deleted in Williams-Beuren syndrome, a neurodevelopmental disorder affecting multiple systems.
同义词
Cep-r; claudin 4; CLAUDIN4; claudin-4; CLDN4; Clostridium perfringens enterotoxin receptor; Clostridium perfringens enterotoxin receptor 1; CPER; CPE-R; CPE-receptor; Cpetr; CPETR1; h CPE-receptor; hCPE-R; WBSCR8; Williams-Beuren syndrome chromosomal region 8 protein
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